WebMay 12, 2024 · Here, we describe the discovery of S-217622, the first oral noncovalent, nonpeptidic SARS-CoV-2 3CL protease inhibitor clinical candidate. S-217622 was … WebFeb 7, 2024 · Shionogi said that new results from an ongoing clinical trial of their pill, known as S-217622, showed a "significant difference" in antiviral effect compared to a placebo, as well as symptom...
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WebMay 5, 2024 · Renal Clearance (CLR) of S-217622 [ Time Frame: 0 (predose) up to 336 hours postdose on Day 1 to Day 15 ] ... Contact: Shionogi Clinical Trials Administrator Clinical Support Help Line: 800-849-9707: [email protected]: Locations. Layout table for location information; WebDec 23, 2024 · This trial will evaluate S-217622, an anti-SARS-CoV2 3C-like protease inhibitor (PI) developed by Shionogi & Co. Ltd. The study design is a randomized, placebo-controlled, multi-center international clinical trial that will evaluate the clinical efficacy of S-217622 when given in addition to standard of care (SOC) for inpatients with COVID-19. ecovacs app funktioniert nicht
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WebMar 25, 2024 · A handout video grab image shows the production process of Shionogi & Co Ltd's ongoing clinical trial of pills, known as S-217622, for the oral coronavirus disease (COVID-19) treatment, in this ... WebJan 26, 2024 · Here, we describe the discovery of S-217622, the first oral non-covalent, non-peptidic SARS-CoV-2 3CL protease inhibitor clinical candidate. S-217622 was discovered via virtual screening followed by biological screening of an in-house compound library, and optimization of the hit compound using a structure-based drug-design strategy. WebApr 25, 2024 · Shionogi has reported late-breaking data from two clinical trials of oral Covid-19 antiviral, S-217622, which concluded in Asia, demonstrated rapid clearance of the virus. An investigational drug for Covid-19, S-217622 is an inhibitor of 3CL protease designed through a research collaboration between Hokkaido University and Shionogi. concerts in wilkes barre scranton